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Medication Supply Disruption Alert: Discontinuation of Morphine Sulphate (MST CONTINUS)

Published On:

1 March 2021

Published In:

Originator: DHSC & NHS England and Improvement: Supply disruption alert


Issue date: Originally issued on 26-Feb-2021 10:06:20. This version was issued on 26-Feb-2021 10:06:20


This alert has been issued to:
  • Care Trusts
  • Mental Health Trusts
  • Specialists Trusts
  • NHS Regional Offices
  • Learning Disabilities Trusts
  • Mental Health & Social Care Trusts
  • Ambulance Trusts
  • Mental Health & Learning Disabilities
  • Acute Trusts
  • Community Trusts
  • MHRA (Medicines) Drug Alerts (Various Recipients)
  • Independent Healthcare Providers (registered with CAS)
  • Clinical Commissioning Groups
  • Social Care Providers (registered with CAS)
  • Special Health Authorities
  • MHRA (Medicines) Drug Alerts – Non-NHS Recipients
  • GP – Locum
  • NHS 111 and Out of hours providers
  • GP Practices
  • DHSC Supply Disruption – Medicines
  • Community Pharmacy
  • Primary Care Networks
  • GP Practices 1
Action category: Action


Title: Discontinuation of Morphine sulphate (MST CONTINUS) 20mg, 30mg, 60mg, 100mg and 200mg prolonged release granules for oral suspension


Broadcast content:
All strengths of MST Continus® prolonged release granules for oral suspension are being permanently discontinued during 2021 due to difficulty sourcing a key excipient.
Alternative morphine presentations, both prolonged release and immediate release, remain available and will be able to support increased demand.
This alert contains further information and action for providers.
Please note that no response is required via the CAS website to this alert.

Additional information:

NHS England and NHS Improvement Regional Offices: Please cascade this alert to Community Pharmacy.

GP Practices please pass on to non-medical prescribers.

Alert reference: SDA/2021/004



To view this alert in full please click HERE

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